Season
- Season 50 2026-03-26
- Season 49 2025-09-26
- Season 48 2024-09-20
- Season 47 2023-09-29
- Season 46 2022-09-23
- Season 45 2021-10-08
- Season 44 2020-10-16
- Season 43 2019-09-27
- Season 42 2018-09-07
- Season 41 2017-09-15
- Season 40
- Season 39
- Season 38
- Season 37
- Season 36 2013-01-04
- Season 35 2012-03-17
- Season 34 2010-09-17
- Season 33
- Season 32 2009-09-11
- Season 31 2008-09-17
- Season 30 2007-09-14
- Season 29 2006-09-08
- Season 28
- Season 26 2003-11-28
- Season 25 2003-05-30
- Season 8 1985-11-07
- Season 2 1979-05-03
- Season 1 1978-06-06
- Season 0
Episode
- Episode 1: Williams Syndrome, Tourettes, Asperger's
- Episode 2: Rutgers - Webcam
- Episode 3: Lotto Frenzy
- Episode 4: OCD, Schizophrenia
- Episode 5: Transgender Beauty Contestant
- Episode 6: Just Plane Crazy
- Episode 7: Strange Arrangements
- Episode 8: Sunset Boulevard
- Episode 9: True Confessions
- Episode 10: Extreme Parenting
- Episode 11: Losing It: The Big Fat Money Trap
- Episode 12: Medical Mysteries
- Episode 13: Friday
- Episode 14: The Jubilee Queen with Katie Couric
- Episode 15: Payback
- Episode 16: The Big Lie
- Episode 17: John Edwards' former mistress
- Episode 18: Caught in a Bad Romance
- Episode 19: Heaven: Where Is It? How Do We Get There?
- Episode 20: Vacation Confidential; My Ultra Modern Family
- Episode 21: The Cammera Never Lies, Tragedy in Colorado
- Episode 22: Chat Room Love Triangle
- Episode 23: What They Know That Can Change Your Life; My Ultra Modern Family
- Episode 24: Friday
- Episode 25: I'm Obsessed With ...
- Episode 26: When Animals Strike Back
- Episode 27: The Camera Never Lies
- Episode 28: Nasty Neighbors
- Episode 29: Intoxication Nation
- Episode 30: Classroom Confidential
- Episode 31: Stalked
- Episode 33: Sandusky Case: Victim 1
- Episode 34: All Access Nashville With Katie Couric
- Episode 35: Heroes
- Episode 36: Workplace Confidential
- Episode 37: The Real Dish
- Episode 38: Breaking Polygamy
- Episode 39: True Confessions
- Episode 40: Holidays Unplugged
- Episode 41: Obama's Interview
20/20 Season 35 Williams Syndrome, Tourettes, Asperger's
Remarkable medical conditions are showcased including children diagnosed with Williams Syndrome, families that must deal with Tourettes Syndrome and inside the mind of Daniel Tammet, one of the world's smartest people diagnosed with Asperger's.
