Season
Episode
- Episode 1: Samantha Bee, Ron Livingston, Portugal. The Man
- Episode 2: Ted Danson, Interpol
- Episode 3: Kevin Hart, Kristen Bell, Hari Nef
- Episode 4: Pete Davidson, Mary Lynn Rajskub, Zainab Johnson
- Episode 5: Kenan Thompson, Jameela Jamil
- Episode 6: Eric McCormack, Sean Casey, Kevin Millar, Amanda Litman
- Episode 7: Molly Shannon, Constance Wu, Nathaniel Rateliff & the Night Sweats
- Episode 8: John Mulaney, Meredith Hagner, Alex Ross
- Episode 9: Ike Barinholtz, Kiernan Shipka, Courtney Barnett
- Episode 10: Wanda Sykes, David Cross, Nafissa Thompson-Spires
- Episode 11: Jonah Hill, Emily VanCamp, The Avett Brothers
- Episode 12: Gerard Butler, Nicolle Wallace, Louie Anderson
- Episode 13: Amanda Peet, Jake Shears
- Episode 14: Wendy Williams, Chris Gethard, Sam Esmail
- Episode 15: Diane Lane, Doug Liman, Cloves
- Episode 16: Michael Moore, Paul Dano
- Episode 17: Claire Foy, Lucas Hedges, boygenius
- Episode 18: Billy Eichner, Soledad O'Brien
- Episode 19: Sarah Jessica Parker, Hallie Jackson
- Episode 20: Tracy Morgan, David Remnick
- Episode 21: Kerry Washington, David Sedaris, Mamoudou Athie
- Episode 22: Jeff Goldblum, Dick Cavett, Mark Iacono
- Episode 23: Stanley Tucci, Kate Bolduan, Pale Waves
- Episode 24: Martin Short, Brian Tyree Henry, Amir Obè
- Episode 25: Sarah Silverman, Jason Mantzoukas, Broods
- Episode 26: John Kerry, Taron Egerton, Daniel Simonsen
- Episode 27: Daniel Radcliffe, Arjen Lubach, Antoni Porowski
- Episode 28: Josh Meyers, Hilary and Larry Meyers
- Episode 29: Michael Douglas, Rufus Wainwright
- Episode 30: Jake Tapper, Bill Burr
- Episode 31: Howie Mandel, Danielle Macdonald, Mehdi Hasan
- Episode 32: Alec Baldwin, Kate Bosworth, Bazzi
- Episode 33: Milo Ventimiglia, Jahana Hayes, Lukas Graham
- Episode 34: Ken Jeong, Vanessa Hudgens, Nicole Byer
- Episode 35: Lenny Kravitz, Anthony Atamanuik
- Episode 36: Natalie Portman, Adam Pally, Pistol Annies
- Episode 37: Saoirse Ronan, Mike Birbiglia, Patrick Droney
- Episode 38: Amy Adams, Stephan James, Nana Kwame Adjei-Brenyah
- Episode 39: John Cena, Rachel Brosnahan, Brian Posehn
- Episode 40: Lin-Manuel Miranda, Colin Quinn
- Episode 41: Chris Hayes, Neal Brennan, Donna Missal
- Episode 42: Neil Patrick Harris, Alessia Cara
- Episode 43: Andy Samberg, Josh Hutcherson
- Episode 44: John Goodman, Julia Garner, Geoffrey Zakarian
- Episode 45: Allison Williams, Ryan Eggold, Sam Richardson
- Episode 46: James McAvoy, D'Arcy Carden, Janelle James
- Episode 47: Jim Gaffigan, Frankie Shaw, A Boogie Wit Da Hoodie
- Episode 48: Michael Strahan, Penn & Teller, Guster
- Episode 49: Colin Jost, Michael Che, Andrea Savage, Death Cab for Cutie
- Episode 50: Connie Britton, Dave Franco, Chris Kelly, Sarah Schneider
- Episode 51: Anne Hathaway, Sen. Sherrod Brown, Michaela Coel
- Episode 52: Ellie Kemper, Claire McCaskill, Young the Giant
- Episode 53: Alan Cumming, Jemele Hill, Maia Mitchell & Cierra Ramirez
- Episode 54: Rosie O'Donnell, Nicolle Wallace, DaniLeigh
- Episode 55: Megan Mullally, Killer Mike, Claire Adam
- Episode 56: Michael Moore, Busy Philipps, Conan Gray
- Episode 57: Jake Tapper, Justina Machado, Marlon James
- Episode 58: Taylor Schilling, Ana Navarro
- Episode 59: Ice-T, Paul Schrader
- Episode 60: J.J. Watt, Tim Meadows, Anna Konkle, Maya Erskine
- Episode 61: Debra Messing, Henry Louis Gates Jr., The Prom
- Episode 62: Don Cheadle, Jake Johnson, Kurt Vile
- Episode 63: Will Forte
- Episode 64: John Mulaney, Stacey Abrams
- Episode 65: John Oliver, Tatiana Maslany, St. Paul & The Broken Bones
- Episode 66: America Ferrera, Desus & Mero, Lauren Alaina
- Episode 67: Natasha Lyonne, Donny Deutsch, Drew Tarver & Heléne Yorke
- Episode 68: James Spader, Glenda Jackson, Brad Leone
- Episode 69: John Legend, April Ryan, Geraldine Viswanathan
- Episode 70: Patton Oswalt, Heidi Gardner, Elle King
- Episode 71: Tyler Perry, Christina Hendricks, Astrid S
- Episode 72: Bernie Sanders, J.K. Simmons
- Episode 73: Jesse Eisenberg, Paula Pell, Dan + Shay
- Episode 74: Paul Giamatti, Jessica Walter, John Hickenlooper
- Episode 75: Ricky Gervais, Asia Kate Dillon, James Bay
- Episode 76: Sharon Horgan & Rob Delaney, Stephanie Schriock
- Episode 77: Oscar Isaac, Winston Duke, Emily King
- Episode 78: Jordan Peele, Phoebe Waller-Bridge, Action Bronson
- Episode 79: Amy Schumer, Natalie Morales, PUP
- Episode 80: Rep. Alexandria Ocasio-Cortez, Andrew Rannells, Carla Lalli Music
- Episode 81: Steve Martin, Susan Kelechi Watson
- Episode 82: Issa Rae, Timothy Simons, Rachael Ray
- Episode 83: Chris Hayes, Rich Eisen, The Strumbellas
- Episode 84: Sen. Kamala Harris, Henry Winkler, Conleth Hill
- Episode 85: Kit Harington, Chelsea Clinton, MARINA
- Episode 86: Timothy Olyphant, Diane von Furstenberg
- Episode 87: Sam Rockwell, Jodie Comer, Kiana Ledé
- Episode 88: Adam Driver, Regina Hall, Anthony Carrigan
- Episode 89: Tracy Morgan, Willie Geist, Ingrid Andress
- Episode 90: Julia Louis-Dreyfus, Mark Hamill, Ashley Longshore
- Episode 91: Hank Azaria, Melissa Fumero, Brandon Maxwell
- Episode 92: Amy Sedaris, Pete Buttigieg, Toro y Moi
- Episode 93: Glenn Howerton, Desi Lydic, Craig Finn
- Episode 94: Seth Rogen, Jared Harris, Lyric Lewis
- Episode 95: Charlize Theron, Tim Robinson, Judah & the Lion
- Episode 96: Adam Sandler, Rep. Will Hurd
- Episode 97: Keri Russell, Ana Gasteyer, Alex Brightman
- Episode 98: Rhea Perlman, Meghan McCain, A R I Z O N A
- Episode 99: Lena Dunham, Ian McShane
- Episode 100: Amy Poehler, Dr. Ruth Westheimer
- Episode 101: Anthony Anderson, Jason Mantzoukas, Rep. Rashida Tlaib
- Episode 102: Bill Hader, Kathryn Newton
- Episode 103: Colin Quinn, Margo Martindale, PKEW PKEW PKEW
- Episode 104: Aidy Bryant, John Waters, Sen. Michael Bennet
- Episode 105: Jeff Daniels, Logan Browning, Ann Beattie
- Episode 106: Bryan Cranston, Eric Stonestreet, Chromeo
- Episode 107: John Lithgow, Beanie Feldstein, Julián Castro
- Episode 108: Olivia Wilde, Christopher Abbott, Janine Brito
- Episode 109: Steve Buscemi, Zosia Mamet, Noah Kahan
- Episode 110: Rachel Maddow, Julio Torres, Ana Fabrega, Fred Armisen
- Episode 111: Jim Gaffigan, Linda Cardellini, Ocean Vuong
- Episode 112: Andy Cohen, Sen. Amy Klobuchar, Regina Spektor
- Episode 113: Kevin Bacon, Cobie Smulders, Jordan Klepper
- Episode 114: Eva Longoria, Jacki Weaver, Michael Torpey
- Episode 115: Aubrey Plaza, Louie Anderson
- Episode 116: Olivia Munn, Ramy Youssef, Matt Maeson
- Episode 117: Tom Holland, Jenny Slate, SOAK
- Episode 118: Terry Crews, Anthony Jeselnik
- Episode 119: Kate McKinnon, Rep. Pramila Jayapal
- Episode 120: Laura Dern, Megan Rapinoe, Catherine Cohen
- Episode 121: Dax Shepard, Nicolle Wallace, Weyes Blood
- Episode 122: Jesse Eisenberg, Emily Deschanel, Kate Tempest
- Episode 123: John Leguizamo, Rep. Hakeem Jeffries, Jonas Brothers
- Episode 124: Sen. Cory Booker, Fred Savage, Kane Brown
- Episode 125: Beto O'Rourke, Retta, Hunter Schafer
- Episode 126: Billy Eichner, Danielle Brooks, Hobo Johnson
- Episode 127: Michael Moore, 2 Chainz, Brian Michael Bendis
- Episode 128: John Oliver, CC Sabathia, Mini Mansions
- Episode 129: Wanda Sykes, Jose Antonio Vargas
- Episode 130: Chris Hayes, Charlamagne tha God
- Episode 131: Chris Cuomo, Gov. Larry Hogan, Rhianne Barreto
- Episode 132: Milo Ventimiglia, Geena Davis, Ex Hex
- Episode 133: Michelle Williams, Noel Gallagher, Tommy Orange
- Episode 134: Amanda Seyfried, Sandra Bernhard, Storm Reid
- Episode 135: Ron Burgundy, Billy Crudup, Robin Thede
- Episode 136: Kathy Griffin, George Takei, Jacqueline Novak
- Episode 137: Danny McBride, Yvonne Strahovski, Marianne Williamson
- Episode 138: Michael Che, Alison Brie, Torche
- Episode 139: Jake Tapper, Mj Rodriguez
- Episode 140: Justice Sonia Sotomayor, Maggie Gyllenhaal, Tatiana Schlossberg
- Episode 141: Tracee Ellis Ross, Maren Morris
- Episode 142: Sen. Bernie Sanders, Julio Torres, DeRay Mckesson
- Episode 143: Kelly Clarkson, Bashir Salahuddin & Diallo Riddle, CJ Hauser
- Episode 144: John McEnroe, Toni Collette, The Hold Steady
- Episode 145: Jennifer Lopez, Michael Sheen, MIKA
- Episode 146: Wendy Williams, Kaitlyn Dever, Eric Holder
- Episode 147: Dax Shepard, Lilly Singh
- Episode 148: John Goodman, Michael C. Hall, Midland
- Episode 149: Chelsea Handler, Sara Gilbert, Tove Lo
- Episode 150: Glenn Howerton, Andrew Yang, Margaret Atwood
Late Night with Seth Meyers Season 6 Wanda Sykes, Jose Antonio Vargas
Actress Wanda Sykes; journalist Jose Antonio Vargas; Jeff Quay sits in with the 8G Band.
